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OverviewZantac 75 is an advanced type of heartburn treatment called an acid reducer. It provides relief by actually reducing the amount of acid your stomach makes. Zantac 75 can also prevent heartburn from occurring if taken 30 to 60 minutes prior to eating food or drinking beverages that can cause heartburn. In the past, heartburn sufferers could only turn to antacids to relieve their symptoms. Antacids just neutralize the acid that is already present in the stomach. In addition, antacids may need to be taken frequently and carry drug interaction warnings.